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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA1
All Species:
22.42
Human Site:
S1146
Identified Species:
44.85
UniProt:
O95477
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95477
NP_005493.2
2261
254286
S1146
L
S
S
C
R
N
S
S
S
T
V
S
Y
L
K
Chimpanzee
Pan troglodytes
XP_001138040
2261
254230
S1146
L
S
S
C
R
N
S
S
S
T
V
S
Y
L
K
Rhesus Macaque
Macaca mulatta
XP_001106713
1081
120445
F89
V
D
G
L
A
L
N
F
Y
E
G
Q
I
T
S
Dog
Lupus familis
XP_538773
2261
253895
S1146
L
S
S
C
R
N
S
S
S
T
V
S
Y
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P41233
2261
253955
S1146
L
S
S
C
R
N
S
S
S
T
V
S
C
L
K
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
H1116
Q
L
V
E
E
L
P
H
E
L
V
L
A
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
S1150
L
S
S
C
R
N
S
S
S
T
V
S
Y
L
K
Chicken
Gallus gallus
NP_989476
2260
254054
S1146
L
S
S
C
R
N
S
S
S
T
V
S
Y
L
K
Frog
Xenopus laevis
NP_001089022
2363
267334
A1243
D
T
G
K
K
D
S
A
S
C
R
S
D
C
S
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
C1226
K
K
E
N
E
C
D
C
A
S
E
C
S
C
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
A713
T
A
G
M
D
P
G
A
R
Q
D
V
Q
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
D891
E
D
I
F
V
S
P
D
T
K
S
S
L
V
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
47
94.9
N.A.
95
50.8
N.A.
89.1
85.4
49.8
51.1
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
100
99.7
47.5
97.6
N.A.
97.3
67.4
N.A.
94.6
92.6
66.8
67.8
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
100
100
0
100
N.A.
93.3
13.3
N.A.
100
100
20
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
13.3
N.A.
100
100
46.6
13.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
17
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
50
0
9
0
9
0
9
0
9
9
17
9
% C
% Asp:
9
17
0
0
9
9
9
9
0
0
9
0
9
0
0
% D
% Glu:
9
0
9
9
17
0
0
0
9
9
9
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
25
0
0
0
9
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
9
9
0
9
9
0
0
0
0
9
0
0
0
9
50
% K
% Leu:
50
9
0
9
0
17
0
0
0
9
0
9
9
59
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
50
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
17
0
0
0
0
0
0
0
9
% P
% Gln:
9
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% Q
% Arg:
0
0
0
0
50
0
0
0
9
0
9
0
0
0
0
% R
% Ser:
0
50
50
0
0
9
59
50
59
9
9
67
9
0
17
% S
% Thr:
9
9
0
0
0
0
0
0
9
50
0
0
0
9
9
% T
% Val:
9
0
9
0
9
0
0
0
0
0
59
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
42
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _